Anti Probiotics?
2018-09-11 21:17:24.684234+00 by Dan Lyke 1 comments
Human gut study questions probiotic health benefits:
Cell: Post-Antibiotic Gut Mucosal Microbiome Reconstitution Is Impaired by Probiotics and Improved by Autologous FMT (PDF). https://doi.org/10.1016/j.cell.2018.08.047
Cell: Personalized Gut Mucosal Colonization Resistance to Empiric Probiotics Is Associated with Unique Host and Microbiome Features. https://doi.org/10.1016/j.cell.2018.08.041
The upshot appears to be that:
- Expelled fecal matter doesn't really give enough information about what bacteria are in the mucosal lining to be a useful diagnostic tool.
- There are some people whose guts will be populated by probiotics, and some whose native gut bacteria will suppress the newly introduced bacteria.
- In the study on repopulation after an antibiotic series, the control group's natural biome repopulated fairly quickly, but for both of the groups that were normally either resistant or not to the probiotic population, the probiotics dominated the gut for a long time. So taking probiotics after antibiotics may actually long-term fuck up your gut biome.