Flutterby™! : Antihistamines and Covid

Antihistamines and Covid

2024-07-07 16:39:44.095329+02 by Dan Lyke 0 comments

Whoah: American Society for Microbiology: Host-Microbial Interactions : Research Article : The histamine receptor H1 acts as an alternative receptor for SARS-CoV-2

To verify whether other antihistamine drugs could also inhibit SARS-CoV-2 infection, we evaluated six first-generation antihistamine drugs, namely, brompheniramine, clemastine, cyproheptadine, diphenhydramine, promethazine, and triprolidine, as well as five second-generation antihistamine drugs, namely, acrivastine, astemizole, azelastine, desloratadine, and loratadine. The PsV inhibition assay showed that all of these antihistamine drugs potentially inhibited SARS-CoV-2 PsVs infection...

https://doi.org/10.1128/mbio.01088-24

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[ related topics: Drugs Health ]

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